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. 2021 Oct 9;19:308. doi: 10.1186/s12951-021-01052-7

Table 1.

Various FePt nanoparticle composite materials are used to enhance their biological applications in MRI

Nanocomposite Particle size Saturation magnetization (Ms) r2 relaxivity (Tesla) Cell types Refs.
FePt-Fe3O4 nanocubes 10–13 nm 26.5 emu·g−1 n/a THP-1 cell line Emo et al. [4]
FePt@Kaolinite nanocomposites 100 ± 10 nm 25.86 emu g−1 17.18 mM−1 s−1 (4.7 T) HepG2 cell line Chan et al. [5]
FePt@MnO nanoparticles 8 ± 1 nm n/a 8.14 mM−1 s−1 (3 T)

HepG2 cell line

MCF-7 cell line

Yang et al. [6]
FePt@iron oxide nanoparticles 14.7 ± 1.1 nm 471 emu cc−1 360 mM−1 s−1 (4.7 T) KB cell line Yang et al. [7]
FePt/SiO2/Au nanoparticles 40 nm 1140 emu cm−3 47 ± 3 mM−1 s−1 (2.35 T) RT4 cell line Kostevšek et al. [8]
FePt@hollow mesoporous silica nanospheres 100–150 nm 9.4 emu g−1 46.2 mM−1 s−1 (9.4 T) HeLa cell line Lin et al. [14]
FePt@mSiO2 87.6 ± 6.5 nm n/a 7.173 mM−1 s−1 (0.47 T) HeLa cell line Chen et al. [15]
FePt-CdS nanoprobe 9–11 nm n/a 538.1 s−1 mg−1 mL RAW 264.7 macrophage cell line Jha et al. [16]
FePt/graphene oxide nanoassemblies 100 nm 4.10 emu g−1 12.425 mM−1 s−1 (3 T)

MCF-7 cell line

normal L02 cell line

Yue et al. [17]

FePt–Fe3O4

core–shell nanoparticles

8 nm 23.1 emu g−1 131.5 mM−1 s−1 (9.4 T) n/a Kim et al. [29]
FePt@Fe2O3 core–shell magnetic nanoparticles 5 nm n/a 91.9 mM−1 s−1 (3 T)

KB cell line

HeLa cell line

Liu et al. [30]
FePt@SiO2 nanoparticles 48.98 ± 6.41 nm  ~ 10 emu g−1 102.3 mM−1 s−1 (3 T) HeLa cell line Lai et al. [35]

Si@FePt- Fe3O4

nanoparticles

 ~ 100 nm  ~ 0.09 emu cm3/mol  ~ 20 mM−1 s−1 n/a Malvindi et al. [36]
FePt@Fe2O3 nanoparticles 8 nm 24.8 emu g−1 3.462 (μg/mL)−1 s−1 (7 T) HeLa cell line Gao et al. [37]

FePt@ Montmorillonite nanocomposites

(This work)

150–200 nm 24.54 emu g−1 41.835 mg−1 s−1 mL (7 T)

SKHep1 cell line

Mahlavu cell line

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