Fig. 3.
Overall structures of GHRH–SV1–Gαs and apo SV1–Gαs complexes. (A) Orthogonal views of the density map (Left) and the model (Right) for the GHRH–SV1–Gαs–Nb35 complex. SV1, GHRH, Gαs, Gβ, Gγ, and Nb35 are colored cornflower blue, gold, light green, salmon, cyan, and gray, respectively. (B) Orthogonal views of the density map (Left) and the model (Right) for the apo SV1–Gαs–Nb35 complex. SV1, Gαs, Gβ, Gγ, and Nb35 are colored slate blue, orange, salmon, cyan, and gray, respectively. The structures are shown in cartoon representation.