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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Biomaterials. 2021 Sep 12;277:121129. doi: 10.1016/j.biomaterials.2021.121129

Figure 6.

Figure 6.

In vivo protective effects of ApoA-I/catalase GIFTed-Exos against CCl4-induced acute liver damage. Mice were intraperitoneally administered with CCl4 (4 mL/kg) dissolved in corn oil (0.5% v/v), followed with immediate intravenous injections of native exosomes or ApoA-I/catalase GIFTed-Exos and two more injections at 6 hours and 12 hours. Enzymatic activities of ALT and AST in plasma were measured 24 hours and 36 hours after CCl4 administration. Value represents mean ± SD (n = 4). ns, not significant; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.