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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Cell Metab. 2021 Apr 2;33(6):1124–1136.e5. doi: 10.1016/j.cmet.2021.03.008

KEY RESOURCES TABLE.

REAGENT or RESOURCE SOURCE IDENTIFIER
Antibodies
Phospho-PRAK-T182 Peiqing Sun - Wake Forest Univeristy
Phospho-p53 (Ser37) Antibody Cell Signaling Technology #9289
p21 Waf1/Cip1 (12D1) Rabbit mAb Cell Signaling Technology #2947
Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody Cell Signaling Technology #9101
p44/42 MAPK (Erk1/2) Antibody Cell Signaling Technology #9102
p38 MAPK Antibody Cell Signaling Technology #9212
Anti-Lamin B1 antibody Abcam ab16048
Anti-HMGB1 antibody Abcam ab18256
Monoclonal Anti-β-Actin antibody Sigma A2228
p53 Antibody (DO-1) Santa Cruz Biotechnology sc-126
Bacterial and Virus Strains
shGFP lentivirus Campisi Lab
shP53 lentivirus Campisi Lab
shPTGDS lentivirus Sigma-Aldrich SHCLNV-NM_000954
Chemicals, Peptides, and Recombinant Proteins
NS-398 Cayman Chemical Company 70590
CAY-10404 Cayman Chemical Company 70210
Ciglitazone Cayman Chemical Company 71730
Troglitazone Cayman Chemical Company 71750
Staurosporine Cayman Chemical Company 81590
Recombinant Human TRAIL protein Abcam ab78818
Arachidonic Acid-d11 Cayman Chemical Company 10006758
Prostaglandin A2 Cayman Chemical Company 10210
Prostaglandin D2 Cayman Chemical Company 12010
Prostaglandin E2 Cayman Chemical Company 14010
Prostaglandin F Cayman Chemical Company 16010
Prostaglandin J2 Cayman Chemical Company 18500
15-deoxy-Δ12,14-Prostaglandin J2 Cayman Chemical Company 18570
1a,1b-dihomo-15-deoxy-Δ12,14-Prostaglandin J2 Jubilant Chemsys P1171
13,14-dihydro-15-keto Prostaglandin D2 Cayman Chemical Company 12610
BW A868C Cayman Chemical Company 12060
OC000459 Cayman Chemical Company 12027
BW 245C Cayman Chemical Company 12050
Hydrocortisone Cayman Chemical Company 20739
Acetic Acid, glacial VWR VW0125–3
Acetonitrile VWR/BDH BDH83639.400
Ammonium acetate Sigma Aldrich 73594–25G-F
LCMS Water Honeywell Burdick & Jackson LC365–4
Methanol Honeywell Burdick & Jackson LC230–4
Chloroform JT Baker 9175–2
Critical Commercial Assays
Baculoviral PPAR-gamma reporter assay Signosis BT-0014
Senescence Detection Kit BioVision K320
15-deoxy-Δ12,14-PGJ2 ELISA Kit ENZO ADI-900–023
Prostaglandin D2-MOX Express ELISA Kit Cayman Chemical Company 500151
IL-6 AlphaLISA PerkinElmer AL223F
Ras Pull-down Activation Assay Biochem Kit Cytoskeleton, Inc BK008-S
Experimental Models: Cell Lines
HEPG2 ATCC HB-8065
IMR-90 ATCC CCL-186
HUVEC-C ATCC CRL-1730
Experimental Models: Organisms/Strains
C57BL/6J The Jackson Laboratory 000664
p16–3MR Campisi Laboratory
Teklad global 18% protein Envigo Teklad 2918
Oligonucleotides
See Table S2
Software and Algorithms
MassHunter Agilent
Other
Kinetex 5μm EVO C18 100Å 150x2.1mm Phenomenex 00F-4633-AN
Data accessibility
Lipid Profiling Dataset National Metabolomics Data Repository (NMDR) PR001093