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Designing DX-based asymmetric and irregular objects with ATHENA. (A) Target geometry and routing model of asymmetric octahedron of 63-bp edge-length. (B) Agarose gel electrophoresis for DX-based asymmetric octahedron. (C) AFM and (D) cryo-EM images of DX-based asymmetric octahedron of 63-bp edge length. (E) 3D reconstruction of DX-based asymmetric octahedron of 63-bp edge length using cryo-EM. Solved structure resolution is 3.3 nm.
