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. 2021 Sep 11;49(18):10397–10418. doi: 10.1093/nar/gkab798

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Comparison with eQTL and chromatin conformation capture experiments. Observed over expected (OE) ratios for the number of unique REMs correctly overlapping annotated regions are obtained in comparison to a background dataset for each method, which is matched in REM sizes, lengths and distances to the TSS of genes. OE ratios using GTEx eQTL data (48) are shown for (A) Blueprint and (B) Roadmap predictions. OE ratios for the number of unique REMs correctly overlapping with Promoter Capture Hi-C data (51) are shown for (C) Blueprint and (D) Roadmap data.