Figure 6.

(A) Genome browser tracks describing the regulation of EGR1. Track C0010KB1 (black) exemplifies the DNase1-seq signal for a sample where EGR1 is expressed, whereas track C005VG11 (gray) illustrates the case where EGR1 is not expressed. (B) Heat map that is clustered according to the DNase1-seq signal in the candidate REMs S1...S10 identified by StitchIt, the gene-expression of EGR1 is not used for the clustering itself and shown for illustration purposes only. The data has been log transformed with a pseudo-count of 1. Two major clusters can be observed corresponding to samples where EGR1 is expressed and to those samples where EGR1 is not expressed. The heatmap shows the log₂ of read counts for DNase1-seq, and log₂ of TPM for gene-expression, respectively.