Table 4.

Common Adverse Events Occurring in ≥10% of Patients

Adverse Event	Any Grade (n=46)	Grade 1–2 (n=37)	Grade 3 (n=6)
Increased alanine aminotransferase	38 (61.3%)	37 (59.7%)	1 (1.6%)
Decreased appetite	35 (56.5%)	35 (56.5%)	0
Increased aspartate aminotransferase	34 (54.8%)	33 (53.2%)	1 (1.6%)
Increased blood bilirubin	22 (35.5%)	21 (33.9%)	1 (1.6%)
Fatigue	18 (29%)	18 (29%)	0
Hypertension	15 (24.2%)	14 (22.6%)	1 (1.6%)
Abdominal pain	12 (19.4%)	12 (19.4%)	0
Diarrhea	8 (12.9%)	7 (11.3%)	1 (1.6%)
Proteinuria	8 (12.9%)	7 (11.3%)	1 (1.6%)
Hand–foot skin reaction	7 (11.3%)	3 (4.8%)	4 (6.5%)