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. 2021 Oct 5;14:5095–5110. doi: 10.2147/JIR.S329972

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© 2021 Zhou et al.

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MHF induced activation of the NLR family, pyrin domain-containing (NLRP)3 inflammasome in the fetal kidney. (A) The qPCR analysis of mRNA levels of genes associated with the inflammasome in the fetal kidney. (B) Expression levels of protein associated with the NLRP3 inflammasome in the fetal kidney. (n = 7–8 per group, *p < 0.05 vs control). (C) IHC of NLRP3 and CD68 and IF staining of CD68 showed the expression and location of NLRP3, and CD68 in the fetal kidney (magnification of 400×; scale bar = 50μm).