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. 2021 Oct 5;16:6783–6796. doi: 10.2147/IJN.S319708

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© 2021 Salem et al.

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Microphotographs of chicken liver: (A–D) Clostridium perfringens- experimentally infected group (Group 1), (E and F) C. perfringens infected group and treated with silver nanoparticles (Group 2), (G) Silver nanoparticles treated group (Group 3), (H) Negative control group (Group 4). (A) Portal vein is severely dilated and engorged with RBCs and surrounded with portal edema and inflammatory cells infiltration (arrow) (HE, x100), (B) Congestion of the hepatic central vein (arrow) (HE, x200), (C) Focal aggregation of mononuclear inflammatory cells in hepatic parenchyma (arrow) (HE,x200), (D) Hepatocytes are showing degenerative changes and dilatation of hepatic sinusoids (HE, x200), (E) Central vein is surrounded with inflammatory cells (arrow) (HE, x200), (F) Hepatic lobule and portal area is showing normal histological pattern (G and H) Normal histological structure of hepatic lobule (HE, x200).