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Topics related to the pharmacokinetics of lipid nanoparticles.
| Active ingredient (Company) |
Patisiran (Alnylam) |
Tozinameran (Pfizer/BioNTech) |
|---|---|---|
| Administration route | intravenous | intramuscular |
| Primary biodistribution | liver | injection site |
| Biodegradable property in ionizable lipid | no | yes |
| Anti-drug antibody (ADA) assessments | anti-PEG antibody | not reported |
