FIGURE 3.

Changes in hepatic lipid levels by Oxy210 treatment. (A) Study design. Female mice carrying human APOE*3‐Leiden and CETP transgenes were fed ad libitum a ‘Western’ high‐fat, high‐cholesterol diet supplemented with Oxy210 (4 mg/g) for 16 weeks. Control mice were fed the same diet without Oxy210 supplementation. (B‐F) Hepatic levels of triglyceride (B), phosphatidylcholine (C), total cholesterol (D), unesterified cholesterol (E) and cholesterol ester (F) are presented as mean ± SD from 8 to 10 mice per group. Abbreviations: CE, cholesterol ester; PC, phosphatidylcholine; TC, total cholesterol; TG, triglyceride; UC, unesterified cholesterol. *denotes p < 0.05 versus control