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. 2021 Oct 9;14:524. doi: 10.1186/s13071-021-05034-4

Table 4.

Predicted prevalence of anemia and its severity after 0.25 and 0.4 mg/kg primaquine

Population Dosing regimen, mg/kg No anemia (Hb > 11–13 g/dl), % All anemia grades (Hb < 11–13 g/dl), % Mild anemia (Hb 7–11 to 11–13 g/dl), % Moderate anemia (Hb 7–8 to 7–11 g/dl), % Severe anemia (Hb < 7–8 g/dl), %
All 0 57.0 43.0 18.3 22.0 2.73
0.25 53.3 46.7 19.6 24.1 2.98
0.40 51.0 49.0 20.1 25.7 3.14
G6PD normal 0 57.4 42.6 18.2 21.7 2.73
0.25 54.1 45.9 19.3 23.7 2.95
0.40 52.0 48.0 19.8 25.1 3.09
G6PD deficient 0 50.4 49.6 19.8 27.1 2.72
0.25 40.5 59.5 24.2 31.9 3.43
0.40 34.8 65.2 25.2 36.1 3.96

The definitions for anemia severity are dependent on age, sex and pregnancy status, and the complete definitions can be found in Additional file 1: Table S1