Table 4.
Population | Dosing regimen, mg/kg | No anemia (Hb > 11–13 g/dl), % | All anemia grades (Hb < 11–13 g/dl), % | Mild anemia (Hb 7–11 to 11–13 g/dl), % | Moderate anemia (Hb 7–8 to 7–11 g/dl), % | Severe anemia (Hb < 7–8 g/dl), % |
---|---|---|---|---|---|---|
All | 0 | 57.0 | 43.0 | 18.3 | 22.0 | 2.73 |
0.25 | 53.3 | 46.7 | 19.6 | 24.1 | 2.98 | |
0.40 | 51.0 | 49.0 | 20.1 | 25.7 | 3.14 | |
G6PD normal | 0 | 57.4 | 42.6 | 18.2 | 21.7 | 2.73 |
0.25 | 54.1 | 45.9 | 19.3 | 23.7 | 2.95 | |
0.40 | 52.0 | 48.0 | 19.8 | 25.1 | 3.09 | |
G6PD deficient | 0 | 50.4 | 49.6 | 19.8 | 27.1 | 2.72 |
0.25 | 40.5 | 59.5 | 24.2 | 31.9 | 3.43 | |
0.40 | 34.8 | 65.2 | 25.2 | 36.1 | 3.96 |
The definitions for anemia severity are dependent on age, sex and pregnancy status, and the complete definitions can be found in Additional file 1: Table S1