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. 2020 Nov 1;72(4):1034–1045. doi: 10.1093/jxb/eraa513

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Fig. 4. — Role of TPXL proteins in cell division. TPX2, TPXL2, and TPXL3 localize to the nuclear envelope, but not to the microtubules of the pre-prophase band during prophase. Aurora kinase also localizes to the nuclear envelope membrane. It is currently not known whether TPXLs and Aurora interact on the nuclear envelope and require each other for this localization. TPXLs function redundantly in promoting nuclear envelope breakdown and mitotic spindle assembly. In the mitotic spindle, TPXLs target Aurora kinase to microtubules and activate it.