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. 2021 Feb 28;106(7):e2673–e2679. doi: 10.1210/clinem/dgab126

Table 3.

Sensitivity and specificity of ß-hydroxybutyrate (> 3 mmol/L and > 3.8 mmol/L) in diagnosing DKA as defined by bicarbonate levels

ß-hydroxybutyrate > 3.0 mmol/L Sensitivity (%) Specificity Sensitivity Specificity
Bicarbonate < 18 mmol/L Bicarbonate < 15 mmol/L
End-stage renal disease 72.2 84.6 86.9 69.2
Moderate renal failure 83.7 54.8 89.3 42.2
Preserved renal function 88.3 43.3 96.2 33.3

Abbreviation: DKA, diabetes ketoacidosis.