Figure 5:

Classification and regression tree analysis revealing three terminal nodes of genomic risk (colored boxes) in patients with initially unresectable colorectal liver metastases who received hepatic arterial infusion and systemic chemotherapy (n=128); PE: parameter estimate; Histogram showing relative proportion of patients in each genomic risk subgroup who converted to resection and were persistently unresectable> Stratification of overall survival by three genomic risk subgroups: co-altered RAS/RAF-TP53, RAS/RAF-altTP53-WT, and RAS/RAF-WT. Number at risk at each time point indicated in adjoining risk table.