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. 2021 Jun 14;23(10):1511–1527. doi: 10.1093/europace/euab092

Table 3.

Summary of baseline characteristics by ABC adherence status for the selected studies

First author (year) Grouped and overall N (%) Age, mean ± SD or median (IQR) Women (%) Hypertension (%) CHA2DS2-VASc, mean ± SD or median (IQR)
Prospective
 Domek (2020)15 ABC 86 (14.3%) 64.8 ± 10.8 44 (51.2%) 69 (80.2%) 3.60 ± 1.27
Non-ABC 517 (85.7%) 63.2 ± 11.9 271 (52.4%) 421 (81.4%) 3.70 ± 1.63
All 603 63.4 ± 11.8 315 (52.2%) 490 (81.3%) 3.69 ± 1.58
 Gumprecht (2020)16 ABC 168 (8.3%) 64.5 ± 12.0 77 (45.7%) 117 (69.6%) 3.01 ± 1.53
Non-ABC 1853 (91.7%) 56.0 ± 16.7 891 (48.1%) 948 (51.2%) 2.28 ± 1.79
All 2021 56.7 ± 16.47 968 (47.9%) 1065 (52.7%) 2.34 ± 1.78
 Guo (2020) 1 year18 mAFA 1646 (49.5%) 67.0 ± 15.0 625 (38.0%) 908 (55.2%) 3 (2–4)
Usual Care 1678 (50.5%) 70.0 ± 12.0 637 (38.0%) 962 (57.3%) 3 (2–4)
All 3324 Not reported 1262 1870 (56.3%) Not reported
 Guo (2020) Extension17 mAFA 1261 (51.0%) 67.8 ± 15.4 34.1% 797 (63.2%) 3 (2–4)
Usual Care 1212 (49.0%) 70.1 ± 12.0 42.1% 776 (64.0%) 3 (2–4)
All 2473 Not reported Not reported Not reported Not reported
 Koziel (2020)12 ABC 1013 (43.8%) 49 (41–57) 485 (47.9%) 898 (88.6%) 3.4 ± 1.8
Non-ABC 1299 (56.2%) 64 (55–71) 557 (42.9%) 882 (67.9%) 3.4 ± 1.9
All 2712 Not reported Not reported Not reported Not reported
Retrospective—post hoc
 Proietti (2018, 2020)21,22 ABC 222 (7.0%) 70 (65–75) 60 (27.0%) 141 (63.5%) 3 (2–4)
Non-ABC 2947 (93.0%) 70 (65–76) 1177 (39.9%) 2102 (71.3%) 2 (1–3)
All 3169 70 (65–76) 1237 (39.0%) 2243 (70.8%) 3 (2–4)
 Pastori (2019)19 ABC 198 (22.4%) 71.7 ± 9.0 48.2% 85.6% 2.56 ± 1.1
Non-ABC 684 (77.6%) 73.5 ± 8.3 38.7% 89.3% 3.7 ± 1.5
All 882 73.1 ± 8.5 40.8% 88.5% 3.50 ± 1.5
Retrospective—registry or electronic health records
 Yoon (2019)14 ABC 31 674 (15.5%) 52.9 ± 12.2 10 129 (32.0%) 5708 (18.0%) 0.91 ± 1.39
Non-ABC 173 168 (84.5%) 64.9 ± 10.8 66 778 (38.6%) 139 411 (80.5%) 2.97 ± 1.80
All 204 842 Not reported Not reported Not reported Not reported
 Proietti (2020) ESC-EHRA20 ABC 1996 (30.0%) 70 (61–76) 741 (37.1%) 1184 (59.7%) 2.68 ± 1.57; 3 (2–4)
Non-ABC 4650 (70.0%) 69 (61–76) 1926 (41.4%) 2693 (58.5%) 3.07 ± 1.90; 3 (2–4)
All 6646 Not reported Not reported Not reported Not reported
 Yang (2020) dementia23 ABC 45 994 (20.2%) 68.8 ± 10.2 18 016 (39.2%) 2425 (5.3%) 0 (0–1)
Non-ABC 182 052 (79.8%) 69.7 ± 11.6 70 218 (38.6%) 117 688 (64.7%) 2 (1–3)
All 228 026 Not reported Not reported Not reported Not reported
 Yang (2020) frailty13 ABC 49 533 (18.8%) 50 (41, 58) 39.4% 7.0% 0 (0–1)
Non-ABC 213 454 (81.1%) 65 (56, 72) 38.6% 65.5% 2 (1–3)
All 262 987 Not reported Not reported Not reported Not reported

ABC, Atrial Fibrillation Better Care; AF, atrial fibrillation; EHRA, European Heart Rhythm Association; ESC, European Society of Cardiology; mAFA, mobile AF-App.