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. 2021 Jun 30;36(9):927–936. doi: 10.1007/s10654-021-00769-x

Table 2.

Results of meta-analyses stratified according to selected characteristics

Characteristic N risk estimatesc RR (95% CI) p-het
Type of asbestos fiber Amosite 6 1.00 (0.74–1.35) 0.43
Chrysotile 16 1.07 (0.81–1.41)
Unspecified 21 1.17 (0.96–1.43)
Geographic region North America 9 1.45 (1.14–1.85) 0.13
Europe 29 1.05 (0.90–1.22)
Others 5 1.15 (0.77–1.72)
Gender Men 31 1.08 (0.96–1.21) 0.10
Women 2 1.10 (0.27–4.42)
Mixed 10 1.12 (0.85–1.47)
Year of first employment  < 1945 21 1.09 (0.90–1.32) 0.001
1945–1960 9 1.47 (1.09–1.99)
 > 1960 10 0.97 (0.85–1.12)
Not specified 3 1.27 (0.76–2.13)

RR, meta-relative risk, based on random-effects model; CI, confidence interval; p-het, p-value of test for heterogeneity of strata-specific RR

cCohort-specific results based on 0 observed events are excluded from the meta-analys