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. 2021 Sep 27;12:690190. doi: 10.3389/fphys.2021.690190

TABLE 2.

The effect of YQ23 on blood gases in hypobaric chamber rabbits.

Treatment time Groups
Plain control Hypobaric chamber YQ23 0.5 g/kg YQ23 0.3 g/kg Rhodiola rosea
PaO2 (mmHg)
1 h 115.3 ± 4.7 64.2 ± 5.6** 93.2 ± 4.2## 97.6 ± 3.7## 72.5 ± 4.5
4 h 62.9 ± 3.8** 97.5 ± 4.6## 96.2 ± 4.2## 70.0 ± 2.7#
12 h 66.3 ± 6.0** 93.3 ± 4.2## 96.8 ± 6.3## 72.6 ± 4.4
24 h 67.2 ± 4.9** 92.1 ± 5.4## 93.6 ± 3.8## 73.7 ± 3.9
SaO2(%)
1 h 97.7 ± 0.7 65.8 ± 3.1** 83.5 ± 5.2## 82.7 ± 5.2## 69.1 ± 6.2
4 h 66.4 ± 5.8** 85.4 ± 2.1## 83.8 ± 5.2## 66.2 ± 2.4
12 h 68.4 ± 7.3** 86.5 ± 4.5## 82.0 ± 4.6## 67.1 ± 3.9
24 h 66.8 ± 3.7** 84.6 ± 5.4## 79.8 ± 5.4## 67.6 ± 6.0
PCO2(mmHg)
1 h 33.7 ± 4.7 30.3 ± 4.0 30.3 ± 5.3 30.2 ± 4.0 30.7 ± 3.7
4 h 30.0 ± 3.6 31.1 ± 5.3 30.0 ± 4.3 29.3 ± 6.5
12 h 31.5 ± 3.9 30.4 ± 4.5 30.0 ± 4.3 29.8 ± 6.4
24 h 32.4 ± 3.6 30.7 ± 4.7 30.1 ± 4.8 29.2 ± 5.3
PH
1 h 7.37 ± 0.02 7.38 ± 0.03 7.38 ± 0.04 7.37 ± 0.03 7.36 ± 0.07
4 h 7.37 ± 0.04 7.37 ± 0.06 7.37 ± 0.03 7.36 ± 0.03
12 h 7.38 ± 0.04 7.38 ± 0.04 7.37 ± 0.03 7.39 ± 0.03
24 h 7.39 ± 0.07 7.38 ± 0.05 7.38 ± 0.05 7.38 ± 0.03
HCO3(mmol/L)
1 h 15.5 ± 2.1 15.7 ± 1.1 14.4 ± 1.3 14.0 ± 3.0 14.4 ± 2.2
4 h 15.4 ± 1.7 15.1 ± 2.4 13.8 ± 3.9 14.8 ± 2.1
12 h 16.1 ± 2.1 14.0 ± 1.7 14.9 ± 2.9 15.3 ± 2.9
24 h 14.6 ± 0.9 13.2 ± 2.2 14.2 ± 1.9 14.1 ± 1.8
BE(mmol/L)
1 h −2.4 ± 1.1 −2.1 ± 0.9 −2.0 ± 1.2 −2.1 ± 1.3 −2.3 ± 1.3
4 h −2.1 ± 1.2 −2.1 ± 0.3 −2.6 ± 1.2 −2.7 ± 1.0
12 h −2.3 ± 1.0 −2.1 ± 0.4 −2.4 ± 1.4 −1.9 ± 1.0
24 h −1.7 ± 0.6 −2.3 ± 0.7 −2.4 ± 0.9 −2.1 ± 0.7
cLac (mmol/L)
1 h 9.3 ± 1.9 10.7 ± 1.1 10.1 ± 1.1 10.0 ± 0.6 9.7 ± 1.8
4 h 11.6 ± 2.1* 9.5 ± 1.0# 9.9 ± 2.1 9.8 ± 1.8
12 h 11.6 ± 1.6* 10.1 ± 1.5 10.5 ± 1.4 9.9 ± 1.2#
24 h 11.5 ± 1.3* 10.5 ± 1.9 10.2 ± 1.0 10.0 ± 1.8

The data are the mean ± SD of n experiments (n = 8). *P < 0.05; **p < 0.01 vs. the plain control; #p < 0.05, ##p < 0.01 vs. the hypobaric chamber group.