TABLE 2.
The effect of YQ23 on blood gases in hypobaric chamber rabbits.
| Treatment time | Groups |
||||
| Plain control | Hypobaric chamber | YQ23 0.5 g/kg | YQ23 0.3 g/kg | Rhodiola rosea | |
| PaO2 (mmHg) | |||||
| 1 h | 115.3 ± 4.7 | 64.2 ± 5.6** | 93.2 ± 4.2## | 97.6 ± 3.7## | 72.5 ± 4.5 |
| 4 h | 62.9 ± 3.8** | 97.5 ± 4.6## | 96.2 ± 4.2## | 70.0 ± 2.7# | |
| 12 h | 66.3 ± 6.0** | 93.3 ± 4.2## | 96.8 ± 6.3## | 72.6 ± 4.4 | |
| 24 h | 67.2 ± 4.9** | 92.1 ± 5.4## | 93.6 ± 3.8## | 73.7 ± 3.9 | |
| SaO2(%) | |||||
| 1 h | 97.7 ± 0.7 | 65.8 ± 3.1** | 83.5 ± 5.2## | 82.7 ± 5.2## | 69.1 ± 6.2 |
| 4 h | 66.4 ± 5.8** | 85.4 ± 2.1## | 83.8 ± 5.2## | 66.2 ± 2.4 | |
| 12 h | 68.4 ± 7.3** | 86.5 ± 4.5## | 82.0 ± 4.6## | 67.1 ± 3.9 | |
| 24 h | 66.8 ± 3.7** | 84.6 ± 5.4## | 79.8 ± 5.4## | 67.6 ± 6.0 | |
| PCO2(mmHg) | |||||
| 1 h | 33.7 ± 4.7 | 30.3 ± 4.0 | 30.3 ± 5.3 | 30.2 ± 4.0 | 30.7 ± 3.7 |
| 4 h | 30.0 ± 3.6 | 31.1 ± 5.3 | 30.0 ± 4.3 | 29.3 ± 6.5 | |
| 12 h | 31.5 ± 3.9 | 30.4 ± 4.5 | 30.0 ± 4.3 | 29.8 ± 6.4 | |
| 24 h | 32.4 ± 3.6 | 30.7 ± 4.7 | 30.1 ± 4.8 | 29.2 ± 5.3 | |
| PH | |||||
| 1 h | 7.37 ± 0.02 | 7.38 ± 0.03 | 7.38 ± 0.04 | 7.37 ± 0.03 | 7.36 ± 0.07 |
| 4 h | 7.37 ± 0.04 | 7.37 ± 0.06 | 7.37 ± 0.03 | 7.36 ± 0.03 | |
| 12 h | 7.38 ± 0.04 | 7.38 ± 0.04 | 7.37 ± 0.03 | 7.39 ± 0.03 | |
| 24 h | 7.39 ± 0.07 | 7.38 ± 0.05 | 7.38 ± 0.05 | 7.38 ± 0.03 | |
| HCO3–(mmol/L) | |||||
| 1 h | 15.5 ± 2.1 | 15.7 ± 1.1 | 14.4 ± 1.3 | 14.0 ± 3.0 | 14.4 ± 2.2 |
| 4 h | 15.4 ± 1.7 | 15.1 ± 2.4 | 13.8 ± 3.9 | 14.8 ± 2.1 | |
| 12 h | 16.1 ± 2.1 | 14.0 ± 1.7 | 14.9 ± 2.9 | 15.3 ± 2.9 | |
| 24 h | 14.6 ± 0.9 | 13.2 ± 2.2 | 14.2 ± 1.9 | 14.1 ± 1.8 | |
| BE(mmol/L) | |||||
| 1 h | −2.4 ± 1.1 | −2.1 ± 0.9 | −2.0 ± 1.2 | −2.1 ± 1.3 | −2.3 ± 1.3 |
| 4 h | −2.1 ± 1.2 | −2.1 ± 0.3 | −2.6 ± 1.2 | −2.7 ± 1.0 | |
| 12 h | −2.3 ± 1.0 | −2.1 ± 0.4 | −2.4 ± 1.4 | −1.9 ± 1.0 | |
| 24 h | −1.7 ± 0.6 | −2.3 ± 0.7 | −2.4 ± 0.9 | −2.1 ± 0.7 | |
| cLac (mmol/L) | |||||
| 1 h | 9.3 ± 1.9 | 10.7 ± 1.1 | 10.1 ± 1.1 | 10.0 ± 0.6 | 9.7 ± 1.8 |
| 4 h | 11.6 ± 2.1* | 9.5 ± 1.0# | 9.9 ± 2.1 | 9.8 ± 1.8 | |
| 12 h | 11.6 ± 1.6* | 10.1 ± 1.5 | 10.5 ± 1.4 | 9.9 ± 1.2# | |
| 24 h | 11.5 ± 1.3* | 10.5 ± 1.9 | 10.2 ± 1.0 | 10.0 ± 1.8 | |
The data are the mean ± SD of n experiments (n = 8). *P < 0.05; **p < 0.01 vs. the plain control; #p < 0.05, ##p < 0.01 vs. the hypobaric chamber group.