TABLE 2.
Clinical and demographics features of paediatric patients in which at least one CPA for antimicrobial dosing adjustment was performed.
| Demographics and clinical features | No. (%) |
|---|---|
| Age | |
| Median (years; IQR) | 6 (1–16) |
| <1 year | 9 (17.0%) |
| 1–5 years | 13 (24.5%) |
| 5–12 years | 15 (28.3%) |
| 12–17 years | 16 (30.2%) |
| Sex | |
| Male | 26 (49.1%) |
| Female | 27 (50.9%) |
| Weight | |
| Median (kg; IQR) | 20 (11.1–31.8) |
| Height | |
| Median (cm; IQR) | 120 (75.3–147) |
| Setting | |
| Neonatology | 5 (9.4%) |
| Paediatric ICU | 19 (35.9%) |
| Paediatric onco-haematology/Transplant Unit | 21 (39.6%) |
| Emergency paediatric ward | 8 (15.1%) |
| Underlying disease | |
| AML | 12 (22.6%) |
| ALL | 9 (17.0%) |
| HAP | 9 (17.0%) |
| Solid neoplasms | 4 (7.5%) |
| Meningo-ventriculitis | 3 (5.7%) |
| Abdominal perforation | 3 (5.7%) |
| Encephalopathy | 3 (5.7%) |
| Neonatal sepsis | 2 (3.8%) |
| CAP | 2 (3.8%) |
| Necrotizing enterocolitis | 2 (3.8%) |
| Others | 4 (7.5%) |
ALL, acute lymphatic leukaemia; AML, acute myeloid leukaemia; CAP, community-acquired pneumonia; HAP, hospital-acquired pneumonia; ICU, intensive care unit; IQR, interquartile range.