Figure 2.

Investigation of the biological neuronal response and the time-matched stimulus at the designed frequency according to the regular-spiking neuron model. The intensity of each external current was set to be the same, while the total current intensity was adjusted to have a reasonable value. The neural response was filtered by a fourth-order Butterworth bandpass filter with cut-off frequencies of 50 and 500 Hz to remove the stimulation artifacts. A 10 Hz oscillation of the membrane potential was observed, which was consistent with the frequency of the interfering stimulation wave. Neuron parameters: length and diameter: L = d = 61.4μm, leak membrane conductance: $g_{\text{leak}}=2.05\times 10^{-5}\text{S}/\text{c}{\text{m}}^2$, reversal potential: E_leak = −70.3mV, maximal conductance: ${\overline{g}}_{\text{Na}}=0.056 \text{S}/{\text{cm}}^2,{\overline{g}}_{\text{Kd}}=0.006 \text{S}/{\text{cm}}^2,{\overline{g}}_M=7.5\times {10}^{-5} \text{S}/{\text{cm}}^2$. Spike threshold: V_T = −56.2mV.