Table 1.

The different effects of NLRP3 inflammasome on bone cells.

Effector cells	Effects	Crosstalk pathways	References
Osteoblasts	Decreased cell migration	ROS	Liu SS et al. (43)
	Inhibited the proliferation and differentiation of osteoblasts	p-AKT and β-catenin	Xu L et al. (49)
Osteoclasts	Enhanced bone-resorption capacity of osteoclasts, but inhibited their efferocytosis	ROS/MAPK/NF-κB pathway	An Y et al. (50)
BMSCs	Inhibits osteogenic differentiation and promotes adipogenic differentiation	SIRT1	Wang L et al. (51)