TABLE 4.

Various angiogenesis-related exosomal non-coding RNAs in GBM.

Cargo	Loci	Expression status	Targets	Model (in vitro, in vivo, humans)	Kind of cells	Reference
linc-POU3F3	chr2: q12.1–q12.1	Up	Endothelial cells	Human, in vitro	A172, U251, U87-MG, 293T, T98G, HBMECs	Lang H. et al., 2017
lncRNA HIF1A	chr12: q24.31–q24.31	Up	HIF−1α	Human, in vitro	U251-MG, U87-MG, T98G, A172	Dai et al., 2019
lincRNA-CCAT2	chr 8: q24.21	Up	VEGFA, TGFβ	Human, in vitro	A172, U251, U87-MG, T98G, 293T, HUVECs	Lang H.-L. et al., 2017
miR-9	chr1: q22–q22	Up	COL18A1, THBS2, PTCH1, PHD3	Human, in vitro, in vivo	A172, U251, U87, BT325, SHG44	Chen X. et al., 2019
miR-26a	chr3: p22.2–p22.2	Up	PTEN	Human, in vitro	SHG-44, BT325, T98G, A172, U251, HEB, HBMECs	Wang et al., 2019
miR-182-5p	chr7: q32.2–q32.2	Up	KLF4, KLF2	Human, in vitro, in vivo	HUVEC, U-251MG, H4, A-172, U-118MG, LN-18, U-87MG	Li et al., 2020
miR-148a-3p	chr7: p15.2–p15.2	Up	ERRFI1	Human, in vitro, in vivo	U-138-MG, U251-MG, LN229, HA, HUVECs	Wang et al., 2020
miR-21	chr17: q23.1–q23.1	Up	VEGF/VEGFR2	In vitro	U-251, hbECs	Sun et al., 2017