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. 2021 Sep 22;149:e213. doi: 10.1017/S0950268821002077

Table 2.

Cluster composition by type of educational institution and role of SARS-CoV-2 index case, Germany, 2020

Characteristic of index case All types of secondary cases (n = 314)a Student/child secondaries (n = 201) Teacher secondaries (n = 113)
N cases (clusters) MSPIb MSPI ratio [95% CI]c P-valuec N cases (clusters) MSPIb MSPI ratio [95% CI]c P-valuec N cases (clusters) MSPIb MSPI ratio [95% CI]c P-valuec
All institutions Student/child, n = 591 145 (76) 0.25 1.00 120 (70) 0.20 1.00 25 (16) 0.04 1.00
Teachers, n = 157 169 (48) 1.08 4.39 [2.67–7.21] <0.001 81 (37) 0.52 2.54 [1.52–4.23] <0.001 88 (32) 0.56 13.25 [6.59–26.67] <0.001
Day-care Student/child, n = 79d 52 (20) 0.66 1.00 30d (15) 0.38 1.00 22d (13) 0.28 1.00
Teachers, n = 113d 142 (38) 1.26 1.91 [0.95–3.84] 0.07 67d (32) 0.59 1.56 [0.78–3.13] 0.21 75d (26) 0.66 2.38 [1.04–5.49] 0.04
Schools Student/child, n = 474d 82 (52) 0.17 1.00 80d (51) 0.17 1.00 2d (2) 0.004 1.00
Teachers, n = 32d 16 (6) 0.50 2.89 [0.99–8.44] 0.05 14d (5) 0.44 2.59 [0.86–7.83] 0.09 2d (2) 0.06 14.81 [2.09–105.15] 0.007

Table displays the mean number of SARS-CoV-2-PCR positive secondary cases per index case (MSPI), conditional on the role of the index case (i.e. student/child vs. teacher), and stratified by type of institution (day-care centre, school). For instance, independent of institution, the mean number of secondary cases in teachers is 0.04 and 0.56 for student/child and teacher-index cases, respectively, corresponding to an MSPI ratio of 13.3; the same comparison for day-care centres results in an MSPI ratio of 2.4.

a

36 index cases with missing age/role information.

b

Mean number of secondary cases per index case (MSPI).

c

MSPI ratio and corresponding confidence intervals (CIs) and P-values from negative binomial regression, modelling the difference in MSPI by category of index case, where an MSPI ratio of 1.0 corresponds to H0 = ‘no difference in the mean count of secondary cases between index categories’.

d

Number of subjects do not add up to total due to exclusion of cases that attended institutions other than schools and day-care centres (e.g. special needs schools).