Table 2.
Variables | Omecamtiv mercabil | Placebo | Relative risk or difference |
---|---|---|---|
(n = 4110) | (n = 4101) | (95% CI) | |
Variation form baseline | |||
Systolic arterial pressure | |||
Week 24 | 1.4 ± 15.3 | 1.5 ± 15.6 | −0.1 (−0.9 to 0.6) |
Week 48 | 2.0 ± 16.1 | 1.9 ± 16.0 | 0.2 (−0.6 to 1.0) |
Heart rate | |||
Week 24 | −2.1 ± 12.6 | −0.5 ± 12.8 | −1.6 (−2.2 to − 1.0) |
Week 48 | −2.0 ± 13.1 | −0.2 ± 13.2 | −1.8 (−2.4 to − 1.1) |
Potassium | |||
Week 24 | −0.01 ± 0.57 | −0.01 ± 0.57 | 0.00 (−0.03 to 0.03) |
Week 48 | −0.03 ± 0.59 | −0.02 ± 0.58 | −0.01 (−0.04 to 0.02) |
NT-proBNP | |||
Week 24 | −251 (−1180 to 295) | −180 (−915 to 441) | 0.90 (0.86 to 0.94) |
Troponin I | |||
Week 24 | 4 (−2 to 21) | 0 (−9 to 8) | 4 (3 to 5) |
Week 48 | 2 (−4 to 18) | 0 (−9 to 8) | 2 (1 to 3) |