Table 2.
Comparison of mGBMs and uGBMs.
| Clinical features | mGBMs | uGBMs | P value | ||||
|---|---|---|---|---|---|---|---|
| No. | % | No. | % | ||||
| Sex | 0.908 | ||||||
| Male | 45 | 78.9 | 24 | 80 | |||
| Female | 12 | 21.1 | 6 | 20 | |||
| Age (years) | 0.425 | ||||||
| Mean | 55.3 | 53.7 | |||||
| SD | 8.9 | 8.1 | |||||
| Pre-op KPS | 0.745 | ||||||
| ≤ 80 | 36 | 63.2 | 20 | 66.7 | |||
| > 80 | 21 | 36.8 | 10 | 33.3 | |||
| Tumor size (cm3) | 0.394 | ||||||
| Mean | 21.8 | 19.4 | |||||
| SD | 13.3 | 11.7 | |||||
| Ki-67 | 0.975 | ||||||
| < 50% | 34 | 59.6 | 18 | 60.0 | |||
| > 50% | 23 | 40.4 | 12 | 40.0 | |||
| MGMT promoter | 0.206 | ||||||
| Methylated | 29 | 50.9 | 11 | 36.7 | |||
| Unmethylated | 28 | 49.1 | 19 | 63.3 | |||
| CD8+ TILs (/HPF) | |||||||
| Mean | 4.82 | 4.82 | 8.11 | 0.002 | |||
| SD | 3.12 | 4.82 | |||||
MGMT, O(6)-methylguanine-DNA-methyltransferase; mGBM, multifocal and multicentric glioblastoma; pre-op KPS, preoperative Karnofsky performance status; TILs, tumor-infiltrating lymphocytes; uGBM, unifocal GBM.