FIGURE 5.

Viral RNA load and isolation for cell culture of challenged animals. The PCR results of nasal swabs (A) and oral swabs (C), and the virus isolated for cell culture from clinical samples from vaccinated and unvaccinated hamsters after challenge with wild homologous SARS-CoV-2 virus (B: nasal swabs; D: oral swabs). Ct values between 10 and 33 are positive, while Ct values ≥ 33.1 are negative; 42 indicates the vaccinated group challenged at 42 days after vaccination, 6 indicates the vaccinated group challenged 6 months after vaccination. ns indicates no significance.