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. 2021 Sep 27;12:720437. doi: 10.3389/fmicb.2021.720437

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Copyright © 2021 Zhugunissov, Zakarya, Khairullin, Orynbayev, Abduraimov, Kassenov, Sultankulova, Kerimbayev, Nurabayev, Myrzakhmetova, Nakhanov, Nurpeisova, Chervyakova, Assanzhanova, Burashev, Mambetaliyev, Azanbekova, Kopeyev, Kozhabergenov, Issabek, Tuyskanova and Kutumbetov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The presence and concentration of virulent virus in the lungs of vaccinated and unvaccinated hamsters. This figure shows data from the 3rd, 5th, 7th, 9th, 12th, and 14th DPI with the wild homologous SARS-CoV-2 virus, specifically the genomic RNA in the lungs (A), and virus isolation from the lungs in Vero cells. (B) Ct values between 10 and 33 are positive, while Ct values ≥ 33.1 are negative; 42 indicates the vaccinated group at 42 days after vaccination; 6 indicates the vaccinated group challenged 6 months after vaccination; ns indicates no significance; DPI, days post infection.