TABLE 1.
Average values (M ± SD) of hematological blood parameters of vaccinated hamsters after administration of the QazCovid-in vaccine candidate.
| Parameters |
Animal groups (n = 20)
|
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|
Placebo
|
Vaccinated
|
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| M (n = 5) | F (n = 5) | M (n = 5) | F (n = 5) | |
| RBC (× 106 cells/μL) | 7.7 ± 1.8 | 8.0 ± 2.1 | 7.6 ± 1.1 | 7.8 ± 1.1 |
| WBC (× 109 cells/μL) | 7.6 ± 2.7 | 7.7 ± 2.3 | 7.2 ± 3.0 | 8.3 ± 4.3 |
| Plat (× 109 cells/μL) | 37.0 ± 12.5 | 40.1 ± 11.4 | 37.3 ± 9.1 | 43.1 ± 8.7 |
| Hb (g/dL) | 15.9 ± 2.3 | 14.8 ± 1.7 | 16.4 ± 2.5 | 14.4 ± 2.8 |
| Hct | 45.7 ± 6.1 | 44.9 ± 8.2 | 42.6 ± 9.1 | 41.3 ± 8.1 |
| MCH | 59.6 ± 8.1 | 58.4 ± 11.2 | 60.5 ± 13.2 | 60.1 ± 10.2 |
| MCHC | 34.8 ± 5.7 | 36.8 ± 5.4 | 35.9 ± 7.1 | 35.9 ± 7.1 |
| Neut (× 109 cells/μL) | 1.7 ± 1.1 | 1.7 ± 1.1 | 1.8 ± 1.3 | 1.8 ± 1.9 |
| Mono (× 109 cells/μL) | 0.9 ± 0.9 | 0.9 ± 0.9 | 1.0 ± 0.7 | 1.1 ± 0.9 |
| Lymp (× 109 cells/μL) | 4.6 ± 2.7 | 4.6 ± 2.7 | 6.3 ± 2.7 | 5.8 ± 2.9 |
| Eos (× 109 cells/μL) | 0.4 ± 2.2 | 0.3 ± 2.2 | 0.3 ± 2.9 | 0.4 ± 2.9 |
| Baso (× 109 cells/μL) | 0.02 ± 0.40 | 0.02 ± 0.20 | 0.03 ± 0.90 | 0.03 ± 0.80 |
M, male; F, female; RBC, red blood cells; WBC, white blood cells; Plat, platelets; Hb, hemoglobin; Hct, hematocrit; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; Neut, neutrophils; Mono, monocytes; Lymp, lymphocytes; Eos, eosinophils; Baso, basophils.