Table 2.

Top 25 upregulated proteins induced by SVV infection in PK-15 cells

Accession no.	Protein	Fold change	p	Functions
gi|311271633	KIF11	10	2.20E-16	Microtubule motor activity
gi|350592923	Lipn	8.89	2.06E-10	Hydrolase activity
gi|37039803	env	7.47	3.14E-08	Unknown
gi|154147577	MDA5	5.62	6.54E-12	RNA helicase activity
gi|47523214	RSAD2	4.33	7.75E-13	Metal ion binding activity
gi|545892076	ISG15	4.24	4.99E-13	Ubiquitin protein ligase binding
gi|324123893	IFIT3	3.97	4.75E-09	RNA-binding activity
gi|72535208	OAS2	3.56	1.05E-12	2′-5′-oligoadenylate synthetase activity
gi|965785153	TTC40	3.3	0.002734	Cilium movement
gi|112790143	IRF7	3.06	4.51E-11	DNA-binding transcription factor activity
gi|206557741	MX2	3.05	9.69E-12	GTPase activity
gi|346986269	IFIT1	3	5.54E-11	Inhibiting expression of viral messenger RNAs
gi|350597057	TRIM5	3	6.17E-13	Ubiquitin–protein transferase activity
gi|72535194	OASL	2.96	1.53E-10	Double-stranded RNA–binding activity
gi|311250760	IFITM1	2.96	0.000443	Preventing viral fusion
gi|350588476	CASP13	2.91	4.00E-08	Cysteine-type endopeptidase activity
gi|545867461	MX1	2.83	7.06E-12	GTPase activity
gi|822599445	OAS1	2.76	1.19E-10	2′-5′-oligoadenylate synthetase activity
gi|545835544	IFI44-isoform X1	2.72	4.46E-15	Carbohydrate derivative–binding activity
gi|744614199	MCL1	2.53	1.58E-10	Protein transmembrane transporter activity
gi|311273188	SP140	2.49	1.19E-09	DNA-binding transcription factor activity
gi|350539097	UBE2L6	2.49	2.38E-12	Ubiquitin–protein transferase activity
gi|744587828	PRODH	2.44	1.68E-09	Proline dehydrogenase activity
gi|395147196	IFIT2	2.4	6.00E-11	Inhibiting expression of viral messenger RNAs
gi|594676074	LGALS3BP	2.35	7.20E-14	Scavenger receptor activity