Table 4.
Top 25 downregulated proteins induced by SVV infection in PK-15 cells
| Accession no. | Protein | Fold change | p | Functions |
|---|---|---|---|---|
| gi|927109764 | MAP4K4 | 0.42 | 2.71E-08 | Creatine kinase activity |
| gi|350578534 | HERC1 | 0.61 | 1.36E-05 | Ubiquitin–protein transferase activity |
| gi|311267396 | GSDMA | 0.65 | 1.46E-05 | Phosphatidylserine-binding activity |
| gi|335301427 | DEPDC5 | 0.68 | 3.73E-06 | GTPase activator activity |
| gi|311258138 | NDUFA3 | 0.68 | 7.90E-05 | NADH dehydrogenase activity |
| gi|927130383 | XPOT | 0.68 | 1.14E-06 | Ran GTPase binding activity |
| gi|927171020 | BANK1 | 0.69 | 0.000252 | Signaling receptor binding |
| gi|311273225 | ALPI | 0.7 | 7.51E-07 | Alkaline phosphatase activity |
| gi|149063967 | Pck2 | 0.72 | 0.001552 | Phosphoenolpyruvate carboxykinase activity |
| gi|350592831 | ZSWIM8 | 0.73 | 0.004609 | Zinc ion–binding activity |
| gi|507652967 | TXNDC9 | 0.73 | 0.000768 | Cadherin-binding activity |
| gi|148231384 | TMSB10 | 0.74 | 9.12E-05 | Organization of the cytoskeleton |
| gi|927221859 | NEB | 0.74 | 0.004553 | Actin filament binding |
| gi|545887817 | KCNJ16 | 0.74 | 0.000348 | Voltage-gated ion channel activity |
| gi|545854656 | TPTE2 | 0.75 | 0.001898 | Protein tyrosine phosphatase activity |
| gi|350593017 | MGEA5 | 0.75 | 7.19E-08 | Hyalurononglucosaminidase activity |
| gi|114326214 | HN1 | 0.75 | 1.08E-07 | Inhibiting AR-signaling pathway |
| gi|927174867 | PRSS23 | 0.75 | 0.000521 | Serine-type endopeptidase activity |
| gi|575471149 | FAU | 0.76 | 2.15E-05 | Structural constituent of ribosome |
| gi|298160948 | COX6A1 | 0.76 | 0.000674 | Oxidoreductase activity |
| gi|594666899 | TSPAN6 | 0.76 | 0.000127 | Regulation of cell development, activation, growth, and motility |
| gi|335285169 | VAMP8 | 0.77 | 0.000871 | Chloride channel inhibitor activity |
| gi|504183227 | PCCB | 0.77 | 0.000532 | Acetyl-CoA carboxylase activity |
| gi|927096865 | ATP9B | 0.77 | 0.003652 | Magnesium ion binding |
| gi|927096791 | ALDH1A3 | 0.77 | 0.000101 | Retinal dehydrogenase activity |