Table 2:

ADRB2 genotype and haplotype data

Characteristics	BREATHE	ESTATe	Follow MAGICS	GALAII	PACMAN	PAGES	PASS	SAGE	SLOVENIA	SCSGES
Subjects with data on rs1042713. n.	998	101	167	1,618	791	720	384	740	212	170
Risk allele (Arg) frequency	0.37	0.34	0.38	0.44	0.41	0.37	0.37	0.51	0.37	0.55
rs1042713 genotype, no. (%)
Arg/Arg	154 (15.4)	14 (13.9)	25 (15.0)	306 (18.9)	124 (15.7)	101 (14.1)	59 (15.4)	198 (26.7)	35 (16.5)	46 (27.0)
Arg/Gly	436 (43.7)	40 (39.6)	78 (46.7)	819 (50.6)	402 (50.8)	330 (45.8)	167 (43.5)	355 (48.0)	87 (41.0)	96 (56.5)
Gly/Gly	408 (40.9)	47 (46.5)	64 (38.3)	493 (30.5)	265 (33.5)	289 (40.1)	158 (41.1)	187 (25.3)	90 (42.5)	28 (16.5)
Subjects with data on rs1042714. n.	998	101	167	1,622	791	722	384	744	212	169
Risk allele (Gln) frequency	0.56	0.60	0.58	0.78	0.63	0.56	0.54	0.82	0.60	0.93
rs1042714 genotype, no. (%)
Gln/Gln	307 (30.8)	36 (35.6)	57 (34.1)	971 (59.9)	313 (39.6)	232 (32.1)	115 (30.0)	497 (66.8)	81 (38.2)	144 (85.2)
Gln/Glu	495 (49.6)	50 (49.5)	79 (47.3)	576 (35.5)	376 (47.5)	349 (48.4)	184 (47.9)	223 (30.0)	91 (42.9)	25 (14.8)
Glu/Glu	196 (19.6)	15 (14.9)	31 (18.6)	75 (4.6)	102 (12.9)	141 (19.5)	85 (22.1)	24 (3.2)	40 (18.9)	0 (0.0)
Subjects with data on both SNPs. n.	998	101	167	1,618	791	714	384	740	212	169
Haplotype frequency
Arg16/Gln27	0.37	0.34	0.38	0.44	0.41	0.37	0.37	0.51	0.37	0.55
Gly16/Gln27	0.18	0.27	0.20	0.34	0.22	0.19	0.17	0.31	0.23	0.37
Gly16/Glu27	0.45	0.39	0.42	0.22	0.37	0.44	0.46	0.18	0.40	0.08
Linkage disequilibrium between rs1042713 and rs1042714
r2 (D`)	0.47 (~1)	0.33 (1)	0.43 (0.98)	0.23 (1)	0.40 (~1)	0.46 (~1)	0.50 (~1)	0.23 (1)	0.40 (1)	0.10 (1)