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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Acta Neuropathol. 2020 Oct 24;141(1):1–24. doi: 10.1007/s00401-020-02235-6

Table 1.

Definitions of Arteriolosclerosis

Source Arteriolosclerosis definition
Skrobot et. al., 2016 Hyaline thickening of walls of vessels <150 μm in diameter, not associated with lipid-containing cells replacing the tunica media. Diagnosis requires an absence of intramural inflammation, amyloid or fibrinoid necrosis.
Buchman et. al., 2013 Arteriolosclerosis describes the histologic changes commonly found in the deep penetrating small vessels of the brain in aging, including intimal deterioration, smooth muscle degeneration, and fibrohyalinotic thickening of arterioles with consequent narrowing of the vascular lumen.
Grinberg and Thal, 2010 Concentric hyaline thickening of small arteries (40 – 150 μm in diameter) leading to a concentric stenosis of the vessel lumen.
Taber’s Medical Dictionary, June 2020 A disease of the arterial vessels marked by thickening and loss of elasticity in the arterial walls. It is known colloquially as “hardening of the arteries.”
Merriam-Webster Medical Dictionary, June 2020 Thickening of the intima of arterioles (as of the kidney in hypertension) by hyaline and fatty deposits that reduce the lumen and obstruct blood flow