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. 2021 Oct 11;18(11):2560–2562. doi: 10.1038/s41423-021-00776-8

Fig. 1. The “seesaw effect” between the early strain and Delta strain in the neutralizing titer of respective convalescent sera.

Fig. 1

a Normalized OD450 nm values of the anti-IgG to the different S proteins were compared between early convalescent serum (n = 22) and Delta convalescent serum (n = 17) samples. b The NT50 of each early convalescent serum against each pseudotyped virus (n = 22). c NT50 of each Delta convalescent serum against each pseudotyped virus (n = 17). d Each convalescent serum sample was serially diluted tenfold and incubated with 400 FFU of authentic SARS-CoV-2 (D614/B.1.617.2), followed by incubation with Vero E6 cells. The FRNT spots of each well were counted. The FRNT50 of nAbs of each convalescent serum was determined by FRNT and is represented as the IC50. The p value was calculated using one-way ANOVA with Tukey’s multiple comparisons test *p < 0.05, ***p < 0.001. Data are represented as the mean ± SD (n = 17 or 22).