Table 4.
Biomarkers assessed as screening tool (number of OGTT avoidable)
| Author—year | Ref N | Biomarker | Diagnostic criteria | Screening threshold value (sensitivity %) | Diagnostic cut-off value (specificity %) | OGTT avoided |
|---|---|---|---|---|---|---|
| Trujillo 2014 | [15] | Fasting blood glucose (FBG) | IADPSG |
A = 4.4 mmol⁄ l (96.9%) B = 4.7 mmol⁄ l (92.5%) |
5.1 mmol⁄ l (100%) |
A = 61.3% B = 81.3% |
| Ruetschi 2016 | [31] | Fasting blood glucose (FBG) | IADPSG | 4.4 mmol⁄ l (78.5%) | 5.1 mmol/l (100%) | 63.8% |
| Renz 2015 | [36] | Glycated haemoglobin (HbA1C) | WHO 1999 | 5.8% (26.4%) | 6.5% (100%) | B = 38% |
| Rajput 2012 | [34] | Glycated haemoglobin (HbA1C) | ADA/IADPSG | 5.45% (85.7%) | 5.95% (97.2%) | 61.8% |