Table 5.
Effect size of two types of anaesthesia on LOS (Days) in prespecified and exploratory subgroups in Each Subgroup
| Anaesthesia | LOS (Days) | |||
|---|---|---|---|---|
| N | β | 95%CI | Interaction P-value | |
| Age (years) group | 0.0072 | |||
| < 60 | 472 | 0.45 | (− 0.03, 0.92) | |
| > =60, < 70 | 1011 | 0.56 | (− 0.07, 1.20) | |
| > =70, < 80 | 744 | 1.99 | (1.15, 2.83) | |
| > =80 | 139 | 2.46 | (−0.29, 5.20) | |
| Sex | 0.0588 | |||
| Female | 1794 | 0.62 | (0.19, 1.05) | |
| Male | 572 | 1.58 | (0.49, 2.67) | |
| Ethnicity | 0.8872 | |||
| Chinese | 1987 | 0.86 | (0.38, 1.34) | |
| Malay | 169 | 0.78 | (−0.04, 1.60) | |
| Indian | 137 | 0.40 | (− 0.53, 1.32) | |
| Others | 73 | 1.53 | (−0.46, 3.52) | |
| BMI group | 0.0067 | |||
| < 25 | 726 | 1.87 | (1.06, 2.67) | |
| > =25, < 30 | 963 | 0.28 | (−0.36, 0.93) | |
| > =30, < 35 | 467 | 0.38 | (−0.26, 1.01) | |
| > =35 | 153 | 0.96 | (−0.17, 2.09) | |
| ASA Status | 0.5077 | |||
| 1 | 161 | −0.01 | (− 0.74, 0.73) | |
| 2 | 2058 | 0.84 | (0.46, 1.21) | |
| 3 | 147 | 1.16 | (0.46, 1.21) | |
| Hb(g/dL) group | 0.9170 | |||
| < 11 | 164 | 1.08 | (−1.04, 3.19) | |
| > =11, < 13 | 888 | 0.92 | (0.17, 1.67) | |
| > =13 | 1314 | 0.79 | (0.32, 1.26) | |
| duration of surgery (mins) group | 0.5324 | |||
| < 60 | 320 | 1.00 | (0.28, 1.72) | |
| > =60, < 120 | 1903 | 0.72 | (0.25, 1.18) | |
| > =120 | 143 | 1.63 | (−0.77, 4.03) | |
| Smoking | 0.1232 | |||
| No | 2141 | 0.93 | (0.48, 1.37) | |
| Yes | 225 | −0.23 | (−1.13, 0.68) | |
| OSA | 0.5106 | |||
| No | 2152 | 0.88 | (0.43, 1.32) | |
| Yes | 214 | 0.39 | (−0.40, 1.18) | |
| DM | 0.2677 | |||
| No | 1920 | 0.72 | (0.30, 1.15) | |
| Yes | 446 | 1.32 | (0.12, 2.51) | |
| IHD | 0.0002 | |||
| No | 2239 | 0.65 | (0.25, 1.05) | |
| Yes | 127 | 4.05 | (1.07, 7.02) | |
| CCF | 0.0423 | |||
| No | 2348 | 0.91 | (0.52, 1.29) | |
| Yes | 18 | −5.88 | (−36.03, 24.28) | |
| CVA | 0.3150 | |||
| No | 2321 | 0.81 | (0.39, 1.23) | |
| Yes | 45 | 2.34 | (0.34, 4.33) | |
| Creatinine > 2 mg/dl | < 0.0001 | |||
| No | 2090 | 1.06 | (0.64, 1.47) | |
| Not recorded | 258 | −0.43 | (−1.55, 0.68) | |
| Yes | 18 | −7.68 | (−26.62, 11.27) | |
| DM on insulin | 0.1413 | |||
| No | 1764 | 1.07 | (0.57, 1.57) | |
| Not recorded | 563 | 0.09 | (−0.62, 0.79) | |
| Yes | 39 | 1.04 | (−1.10, 3.17) | |
| Day of week of operation | 0.1282 | |||
| Monday | 390 | 1.08 | (−0.34, 2.49) | |
| Tuesday | 539 | 0.37 | (−0.29, 1.04) | |
| Wednesday | 405 | 0.40 | (−0.28, 1.08) | |
| Thursday | 533 | 0.60 | (0.01, 1.18) | |
| Friday | 378 | 2.08 | (0.60, 3.57) | |
| Saturday | 121 | 0.15 | (−0.69, 0.99) | |
Abbreviations: LOS Length of stay, ASA American Society of Anesthesiologist Physical Status, OSA Obstructive sleep apnea, DM Diabetes mellitus, IHD Ischaemic heart disease, CCF Congestive cardiac failure, CVA Cerebrovascular accidents