Fig. 5.

Therapeutic effect of VPA on SARS-CoV-2 and VSV-GFP yields. a Schematic of the experiment to determine the therapeutic effect of VPA on viral yield. HK-2 and Huh-7 cells were infected with SARS-CoV-2 (MOI of 0.5) or VSV-GFP (MOI of 0.01) and 1 hpi, the cells were treated with VPA at 4, 8, and 16 mM, or left untreated (control cells) for an additional 24 h. Virus titers of SARS-CoV-2 (b) and VSV-GFP (c) were determined by a lysis plaque assay and are represented in absolute numbers as plaque-forming units per ml (PFU/ml). Data are represented as the mean ± SD of triplicate experiments. *p < 0.05