FIGURE 6.

SYVN1 enhances cell migration and angiogenesis. (A‐B) LM3 and HUH7 cells infected with lentiviral shNC or shSYVN1 were subjected to a transwell migration assay. (C‐D) HUVECs were cultured on Matrigel‐coated plates with conditioned media from LM3 and HUH7 cells infected with lentiviral shNC or shSYVN1 for 12 h. The relative mesh areas to shNC group were calculated. (E) mRNA expression levels of genes involved in angiogenesis were measured by qPCR in LM3 and HUH7 cells infected with lentiviral shNC or shSYVN1. Error bars represent the standard deviation. * P < 0.05, ** P < 0.01, *** P < 0.001. Abbreviations: NC, negative control