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. Author manuscript; available in PMC: 2022 Apr 8.
Published in final edited form as: J Med Chem. 2021 Mar 25;64(7):3546–3559. doi: 10.1021/acs.jmedchem.0c01930

Figure 5.

Figure 5.

Hepatic disposition models. Abbreviations: CH, hepatic drug concentration; Cin, entering drug concentration; CLH, hepatic clearance; Cout, exiting drug concentration; QH, hepatic blood flow.