Table 2.
Pairwise Comparison of IOP, EVP, Blood Pressure, and Heart Rate at 15 and 60 Minutes of Instillation of Phenylephrine 2.5% With Baseline Among Treated and Control Eyes
| 15 Min | 60 Min | ||||||
|---|---|---|---|---|---|---|---|
| Variable | Baseline Mean ± SD | Mean ± SD | Pairwise Difference From Baseline ± SD | P Value | Mean ± SD | Pairwise Difference From Baseline ± SD | P Value |
| Treated IOP (mm Hg) | 15.0 ± 2.5 | 16.0 ± 2.4 | 1.0 ± 1.2 | 0.001 | 15.0 ± 2.0 | 0.0 ± 1.4 | 0.92 |
| Control IOP (mm Hg) | 14.5 ± 2.0 | 15.1 ± 1.9 | 0.6 ± 1.0 | 0.01 | 14.8 ± 2.0 | 0.3 ± 1.0 | 0.18 |
| Treated EVP (mm Hg) | 8.4 ± 1.7 | 8.3 ± 1.9 | −0.1 ± 1.5 | 0.81 | 7.3 ± 1.9 | −1.1 ± 0.9 | <0.001 |
| Control EVP (mm Hg) | 8.3 ± 2.2 | 8.3 ± 2.4 | 0.0 ± 1.0 | 0.91 | 8.2 ± 2.5 | −0.1 ± 0.9 | 0.68 |
| SBP (mm Hg) | 117.1 ± 16.4 | 118.8 ± 19.5 | 1.7 ± 6.8 | 0.26 | 119.0 ± 21.0 | 1.9 ± 8.8 | 0.35 |
| DBP (mm Hg) | 79.4 ± 8.7 | 81.0 ± 10.0 | 1.6 ± 4.2 | 0.10 | 81.7 ± 10.2 | 2.3 ± 5.4 | 0.07 |
| HR (bpm) | 74.9 ± 10.5 | 73.4 ± 11.9 | −1.5 ± 5.5 | 0.23 | 72.6 ± 11.1 | −2.3 ± 7.1 | 0.15 |
All comparisons were performed using paired t-tests.
DBP, diastolic blood pressure; HR, heart rate; SBP, systolic blood pressure.