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. 2021 Oct 8;9(10):e002995. doi: 10.1136/jitc-2021-002995

Figure 1.

Figure 1

Waterfall plot of ipilimumab–nivolumab for melanoma brain metastases (MBMs). Panel A displays the waterfall plot of first-line ipilimumab–nivolumab (n=24) for MBMs. Panel B displays the waterfall plot of second/third line ipilimumab–nivolumab (n=28) for BRAFV600 mutant MBMs. Note from the first and second/third line ipilimumab–nivolumab groups, one and two patients, respectively, did not have measurable MBMs and were excluded from this analysis. Maroon columns display patients who were treated with SRS or WBRT within 12 weeks prior to commencing ipilimumab–nivolumab. CR, complete response; SRS, stereotactic radiosurgery; WBRT, whole brain radiotherapy.