Table 1.
Differentially expressed proteins in the CSF regulated by both CUMS and ICA
| Accession | Protein name | Gene name | CON/CUMS | ICA/CUMS |
|---|---|---|---|---|
| ENSRNOP00000002394 | Chordin | Chrd | 1.330657 | 1.251991 |
| ENSRNOP00000004386 | Myocilin | Myoc | 1.237837 | 1.321273 |
| ENSRN0P00000012286 | UDP-GlcNAc:betaGalbeta-1,3-N-acetylglucosaminyltransferase 2 | B3gnt2 | 1.346536 | 1.214411 |
| ENSRN0P00000016389 | Transforming growth factor, beta induced | Tgfbi | 1.246915 | 1.206508 |
| ENSRN0P00000027860 | HtrA serine peptidase 1 | Htral | 1.246935 | 1.239292 |
| ENSRN0P00000059194 | Angiopoietin-like 1 | Angptll | 1.294498 | 1.220162 |
| ENSRN0P00000070498 | Carboxypeptidase D | Cpd | 1.320809 | 1.340595 |
| ENSRN0P00000071077 | Collagen type II alpha 1 chain | Col2a1 | 1.836686 | 1.680284 |
| ENSRN0P00000001397 | Transmembrane p24 trafficking protein 2 | Tmed2 | 0.473675 | 0.404166 |
| ENSRN0P00000001518 | Ribosomal protein lateral stalk subunit P0 | RplpO | 0.696513 | 0.706795 |
| ENSRN0P00000004278 | Ribosomal protein S4, X-linked | Rps4x | 0.353676 | 0.372436 |
| ENSRN0P00000004867 | Small ubiquitin-like modifier 2 | Sumo2 | 0.746357 | 0.557202 |
| ENSRN0P00000008509 | Eukaryotic translation initiation factor 1A, X-linked | Eiflax | 0.658648 | 0.648145 |
| ENSRN0P00000009249 | Proteasome 26S subunit, non-ATPase 6 | Psmd6 | 0.550629 | 0.486541 |
| ENSRN0P00000009556 | Heat shock protein HSP 90-alpha | HSP90AA1 | 0.730779 | 0.665003 |
| ENSRN0P00000009649 | Proteasome 26S subunit, ATPase 6 | Psmc6 | 0.718329 | 0.621687 |
| ENSRN0P00000010674 | Tyrosyl-transfer RNA synthetase | Yars | 0.556245 | 0.649364 |
| ENSRN0P00000013375 | Eukaryotic translation initiation factor 2 subunit alpha | Eif2sl | 0.465363 | 0.499192 |
| ENSRN0P00000015598 | RAB11a, member RAS oncogene family | Rablla | 0.730942 | 0.70133 |
| ENSRN0P00000017234 | Heparin binding growth factor | Hdgf | 0.771831 | 0.595331 |
| ENSRN0P00000019162 | Ribosomal protein L35 | Rpl35 | 0.61251 | 0.58689 |
| ENSRN0P00000019247 | Ribosomal protein L27a | Rpl27a | 0.673251 | 0.666698 |
| ENSRN0P00000021048 | Myosin light chain 12A | Myl12a | 0.495839 | 0.518126 |
| ENSRN0P00000022184 | Ribosomal protein S12 | Rps12 | 0.255554 | 0.234153 |
| ENSRN0P00000022603 | Calmodulin 1 | Calml | 0.636832 | 0.5501 |
| ENSRN0P00000023935 | Ribosomal protein S3 | Rps3 | 0.519405 | 0.502597 |
| ENSRN0P00000024430 | Vimentin | Vim | 0.727629 | 0.691827 |
| ENSRN0P00000025217 | Ribosomal protein L17 | Rpl17 | 0.482482 | 0.50053 |
| ENSRN0P00000026528 | Ribosomal protein S5 | Rps5 | 0.414189 | 0.469701 |
| ENSRN0P00000026696 | Heat shock protein family A member 9 | Hspa9 | 0.679796 | 0.621869 |
| ENSRN0P00000027246 | Ribosomal protein S19 | Rps19 | 0.452858 | 0.524735 |
| ENSRN0P00000033144 | Ribosomal protein s25 | Rps25 | 0.364721 | 0.310551 |
| ENSRN0P00000033950 | Ubiquitin-like modifier activating enzyme 1 | Uba1 | 0.787971 | 0.715948 |
| ENSRN0P00000034657 | Ubiquitin-like protein fubi and ribosomal protein S30-like | LOC100360647 | 0.392441 | 0.374892 |
| ENSRN0P00000034846 | Heat shock protein 90 beta family member 1 | Hsp90b1 | 0.735841 | 0.802234 |
| ENSRN0P00000038448 | Seryl-transfer RNA synthetase | SerRS | 0.517425 | 0.483297 |
| ENSRN0P00000044296 | Actin, beta | Actb | 0.783141 | 0.768301 |
| ENSRN0P00000056260 | Ribosomal protein S14 | Rps14 | 0.523183 | 0.572311 |
| ENSRN0P00000060949 | Ribosomal protein L34 | Rpl34 | 0.150869 | 0.172269 |
| ENSRN0P0000006442 | - | AABR07065778.2 | 0.593477 | 0.614344 |
| ENSRN0P0000006633 | - | AABR07065750.2 | 0.581222 | 0.541466 |
| ENSRN0P00000067217 | Histone cluster 1 H2a family member I like 1 | Hist1h2ail1 | 0.491005 | 0.388903 |
| ENSRN0P00000070331 | Protein kinase N3 | Pkn3 | 0.455886 | 0.407136 |
| ENSRN0P00000070868 | Tubulin, alpha 1B | Tuba1b | 0.689164 | 0.596259 |
| ENSRN0P00000071233 | Spectrin, beta, non-erythrocytic 1 | Sptbn1 | 0.670589 | 0.628294 |
| ENSRN0P00000072016 | TATA-box binding protein associated factor 15 | Taf15 | 0.693424 | 0.622737 |
| ENSRN0P00000073493 | RAB1A, member RAS oncogene family | Rab1a | 0.579087 | 0.532868 |
| ENSRN0P00000074005 | Dyskerin pseudouridine synthase 1 | Dkc1 | 0.13148 | 0.139895 |
| ENSRN0P00000074688 | Ubiquitin C | Ubc | 0.733036 | 0.750576 |
| ENSRN0P00000075909 | NFKB activating protein | Nkap | 0.291945 | 0.260421 |
CON: Control; CSF: cerebrospinal fluid; CUMS: chronic unpredictable mild stress; ICA: icariin.