Table 1.

Patient demographics and clinical parameters of entire patient cohort.

	All patients (N = 62)
Age in years, mean (SD)	67.9 (10.6)
Male sex, %(n)	56.5 (35)
Cerebrovascular risk factors
Smoking, %(n)	35.5 (22)
Arterial hypertension, %(n)	79.0 (49)
Diabetes mellitus, %(n)	29.9 (26)
Atrial fibrillation, %(n)	21.0 (13)
Hypolipoproteinemia, %(n)	46.8 (29)
Stroke etiology
Large-artery atherosclerosis, %(n)	33.9 (21)
Cardioembolism, %(n)	30.7 (19)
Small-vessel occlusion, %(n)	14.5 (9)
Stroke of other determined etiology, %(n)	6.5 (4)
Stroke of undetermined etiology, %(n)	12.9 (8)
NIHSS time of acute stroke, mean (SD)	10 (6–14)
Time from stroke onset to first MRI (v01) in days, median (IQR)	27 (15–34)
Time from onset to second MRI (v02) in days, median (IQR)	61 (47–67)
NIHSS at v01, median (IQR)	6 (3–9)
NIHSS at v02, median (IQR)	4 (2–6)
Wahlund score assessed v01, median (IQR)	5 (3–8)
Lesion volume in mL on v01, median (IQR)	32.2 (9.7–86.4)
Treatment group physical fitness, %(n)	49.2 (30)

SD= standard deviation; IQR=interquartile range; MRI =magnetic resonance imaging; v01 = time point first MRI, v02 = time point second MRI.