Table 8.
Comparison of targets in T3-4 NPC patients.
| Median (IQR) | P-value | |||||||
|---|---|---|---|---|---|---|---|---|
| Target | Index | IMRT | VMAT | TOMO | P | I vs. V | I vs. T | V vs. T |
| PGTVnx | V69.96 (%) | 90.00 (87.50-93.00) | 91.00 (90.00-95.00) | 93.61 (91.90-94.83) | 0.037 | 0.495 | 0.033 | 0.741 |
| D2 (Gy) | 76.08 (75.82-76.78) | 76.66 (74.29-78.58) | 75.75 (74.79-76.93) | 0.651 | _ | _ | _ | |
| D50 (Gy) | 72.81 (72.20-73.26) | 72.90 (72.04-74.02) | 73.35 (72.51-73.95) | 0.688 | _ | _ | _ | |
| D95 (Gy) | 68.24 (66.43-69.07) | 67.79 (64.98-69.71) | 69.49 (68.35-69.90) | 0.018 | 1 | 0.016 | 0.192 | |
| D98 (Gy) | 63.92 (60.43-67.14) | 63.53 (58.69-66.58) | 66.89 (61.43-68.12) | 0.06 | _ | _ | _ | |
| CI | 0.490 (0.440-0.540) | 0.500 (0.445-0.540) | 0.507 (0.468-0.574) | 0.165 | _ | _ | _ | |
| HI | 0.160 (0.115-0.225) | 0.190 (0.130-0.245) | 0.135 (0.101-0.197) | 0.091 | _ | _ | _ | |
| PCTV-1 | V59.4 (%) | 98.00 (97.00-99.00) | 98.00 (96.50-99.00) | 98.85 (98.40-99.56) | 0.011 | 1 | 0.192 | 0.016 |
| D2 (Gy) | 75.82 (75.57-76.32) | 76.26 (74.37-78.37) | 75.69 (74.62-76.60) | 0.867 | _ | _ | _ | |
| D50 (Gy) | 72.05 (71.83-72.32) | 72.06 (71.49-72.89) | 72.59 (70.09-73.73) | 0.097 | _ | _ | _ | |
| D95 (Gy) | 62.35 (61.888-63.05) | 62.42 (60.52-63.45) | 63.02 (62.41-64.26) | 0.172 | _ | _ | _ | |
| D98 (Gy) | 59.34 (58.09-60.33) | 58.58 (56.84-60.44) | 60.97 (60.28-62.33) | 0.002 | 1 | 0.021 | 0.003 | |
| CI | 0.360 (0.330-0.405) | 0.380 (0.340-0.445) | 0.430 (0.385-0.480) | <0.001 | 0.228 | <0.001 | 0.021 | |
| PCTV-2 | V54 (%) | 97.00 (95.50-98.00) | 97.00 (96.00-98.00) | 98.27 (96.42-98.98) | 0.003 | 1 | 0.005 | 0.05 |
| D2 (Gy) | 75.23 (74.87-75.62) | 75.06 (73.45-77.32) | 75.03 (74.23-76.17) | 0.717 | _ | _ | _ | |
| D50 (Gy) | 65.15 (63.92-66.81) | 65.72 (64.37-67.17) | 64.24 (62.18-65.63) | 0.002 | 1 | 0.026 | 0.002 | |
| D95 (Gy) | 55.11 (54.73-55.42) | 54.92 (54.63-55.50) | 55.65 (55.03-56.18) | 0.044 | 1 | 0.228 | 0.017 | |
| D98 (Gy) | 52.97 (51.74-54.01) | 52.86 (51.83-54.06) | 54.45 (52.77-55.05) | 0.007 | 0.84 | 0.135 | 0.006 | |
| CI | 0.690 (0.655-0.735) | 0.760 (0.730-0.780) | 0.730 (0.710-0.770) | <0.001 | <0.001 | 0.003 | 0.948 | |
IMRT/I, intensity modulated radiation therapy; VMAT/V, volumetric modulated arc therapy; TOMO/T, tomotherapy; Gy, gray; IQR, inter-quartile range; DV, the absorbed dose in v% of the volume; CI, conformity index; HI, homogeneity index; Vx, the volume of organ receiving more or equal to x Gy.