Figure 1.
Schematic diagram prediction of largemouth bass SIRT1, including NAD+ binding domain, zinc ion binding module and unstructured region (A). Multiple sequence alignment of SIRT1 with deduced amino acid sequences of other fish or mammal animals (B), including Sparus aurata (AHX56273.1), Salmo salar (ENSSSAT00000005225.1), Mus musculus (NP_062786.1) and Homo sapiens (NP_036370.2). The predicted protein domain is indicated by horizontal line, and the substrate binding site, NAD+ binding site and Zn binding site are indicated by the “*”, “#” and “##” at the top of the sequence, respectively.