Fig. 2. Significant phosphorylated peptides and kinases. PHOXTRACK enrichment of known kinase targets from significantly differentiating phosphopeptides from (A) MDA-MB-231 compared to MCF10A, (B) HCC1937 compared to MCF10A, and (C) HCC1937 compared to MDA-MB-231. The PHOXTRACK score displays the predicted activation (red) or inactivation (blue) of a particular kinase in the vertical bar. A selected kinase and its substrates are shown in the horizontal bar plots. The plot displays the log2 ratio for hyper-phosphorylated (red) and hypo-phosphorylated (blue) peptides identified in the phosphoproteomics data set.