Significant histone PTMs.
Histone PTM | log2 fold change (MDA-MB-231 vs. MCF10A) | log2 fold change (HCC1937 vs. MCF10A) | log2 fold change (HCC1937 vs. MDA-MB-231) | PTM modification proteins (WERAM) |
---|---|---|---|---|
H3k9me2 | 0.22 | −1.737 | −1.956 | MECOM, PRDM2,PRDM16, PRDM8, PRDM2, EHMT1, EHMT2, JHDM2A, JMJD2C, JMJD2B, TRIM28 |
H3k9me3 | −3.319 | −4.735 | −1.416 | MECOM, PRDM2, PRDM16, PRDM8, PRDM2, EHMT1, EHMT2, JHDM2A, JMJD2C, JMJD2B, TRIM28 |
H3k36me | 0.883 | 1.579 | 0.696 | WHSC1, NSD1, NSD2, SMYD2, SETMAR, SETD2, ASH1L, METNASE, SETD3 |
H3k79me | 1.601 | 1.905 | 0.304 | DOT1 |
H4k20me | −0.817 | −1.994 | −1.177 | WHSC1, SUV420H1, SUV420H2, SETD8, L3MBBTL1 |