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. 2021 Sep 27;13:717644. doi: 10.3389/fnagi.2021.717644

FIGURE 3.

FIGURE 3

Enriched environment decreased ischemic infarction and inhibited pyroptosis after I/R injury. (A) Schematic brain with a highlight of the ischemic border. (B,D) Representative cresyl violet stained brain slices and quantification of cerebral infarct volume percentage. Scale bars, 5000 μm. n = 6. (C,E) Protein levels of GSDMD-N in peri-infarct tissues. n = 6. (G,F) Representative IHC staining images for GSDMD in the penumbra and IHC score of GSDMD in the penumbra. Scale bars, 50 μm. n = 6. Data are expressed as mean ± SD. *p < 0.05, ***p < 0.001 vs. SSC group; ##p < 0.01, ###p < 0.001 vs. ISC group.