Table 1. Summary of cases of post COVID vaccine myocarditis.

CMRI: cardiac magnetic resonance imaging; NSAID: nonsteroidal anti-inflammatory drug

Study, No of patients (n)	Comorbidities	Associated vaccine	Age (years)	Timing of presentation (post-second dose of vaccine)	Presenting symptoms	ECG	Tn +ive	CMRI changes	Treatment	Prognosis
Habib et al. [1]     N=1	Former smoker	BNT162b2	37/M smoker	36 hours	Squeezing chest pain	Mild ST elevation in anterior leads.	+	Early and late faint subepicardial enhancement of the basal lateral wall.	DAPT, metoprolol.	6-day hospital stay, patient was asymptomatic at discharge.
Jay Montgomery et al. [3] N=23	Healthy	7 received BNT162b2-mRNA; 16 received mRNA-1273 vaccine	20-52/M	Within 96 hours	Sharp chest pain	ST elevations, T wave inversion and nonspecific ST changes were seen in 83% of patients.	+	n=8, which showed SE late gadolinium enhancement and/or focal myocardial edema	Rapid recovery was seen in all patients.	Symptoms resolved in 1 week for 16 patients. Follow-up data wasn’t available for the rest of the seven patients.
Mansour et al. [4] N=2	Healthy	mRNA -1273 for both patients.	21,25 M:F=1:1	Within 48 hours	Sharp retrosternal chest pain	Mild ST elevations and PR depression	+	SE late gadolinium enhancement was seen in both patients.	Beta blocker	Symptoms resolved within 24 hours, no data on long-term follow-up.
Kim et al. [5] N=4	3 males and 1 female	2 received mRNA -1273, 2 received BNT162b2 vaccine	36(M), 23(M), 70(F), 24(M)	Within 2-5 days	Severe chest pain	ST elevations	+	Regional dysfunction, late gadolinium enhancement, and elevated native T1 and T2.	NSAIDs +/- colchicine	Patients discharged within 2-4 days, none requiring rehospitalization.
Muthukumar et al. [6] N=1	HTN, HPLD, OSA.	mRNA 1273 vaccine	52(M)	Within 72 hours	Mid sternal chest discomfort	Left axis deviation, No ST-T changes.	+	Mid myocardial and SE linear and nodular late gadolinium enhancement (LGE) in the inferoseptal, inferolateral, anterolateral, and apical walls.	Low dose Lisinopril and carvedilol. No immunosuppressive or anti-inflammatory medications.	4-day hospital course. No rehospitalization in the following three months.
Ammirati et al. [7] N=1	Healthy	BNT162b2 vaccine	56(M)	Within 72 hours	Acute chest pain	Minimal ST elevation in precordial leads with peaked T waves	+	Focal SE -intramyocardial (non-ischemic pattern) late gadolinium enhancement (LGE) involving the basal and apical segments of the inferolateral wall	Supportive therapy	7-day uncomplicated hospital course.
Abu Mouch et al. [8] N=7	Healthy	BNT162b2 vaccine	Median age: 23(M)	Six patients within 24-72 hours, one patient presented after 15 days.	Chest pain	ST elevation noted in all patients	+	CMR was done in all patients, which was suggestive of myocarditis(myocardial edema and late gadolinium enhancement)	NSAID + Colchicine	Mild hospital course, data not available on long-term follow-up.
Albert et al. [9] N=1	Healthy	mRNA-1273	24(M)	4 days	Chest discomfort	Sinus rhythm, without any ST changes	+	Patchy mid-myocardial and epicardial delayed gadolinium enhancement, with superimposed edema	Unclear	Unclear