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. 2021 Apr 9;14(5):1756–1768. doi: 10.1111/cts.13005

FIGURE 1.

FIGURE 1

Study design of the first‐in‐human assessment of safety, PK and PD effects of remibrutinib. MAD, multiple ascending dose; PD, pharmacodynamic; PK, pharmacokinetic; SAD, single ascending dose